Tesamorelin 10mg

Tesamorelin is a synthetic peptide analog of growth hormone-releasing hormone (GHRH), designed to stimulate the pituitary gland to release endogenous growth hormone (GH).

• Structure: 44-amino-acid peptide analog of human GHRH.
• Purpose: Enhances natural GH secretion, primarily to reduce visceral fat and improve metabolic parameters.
• Regulatory status: FDA-approved for reducing excess abdominal fat in HIV-associated lipodystrophy.

🧪 Clinical Evidence

Primary Use: Tesamorelin is FDA-approved for HIV-associated lipodystrophy, which causes redistribution of fat (especially in the abdomen).

Efficacy: Clinical trials show:

•Significant reduction of visceral adipose tissue (VAT) after 26–52 weeks of treatment.

•Some improvement in waist circumference and metabolic markers.

•GH-dependent side effects are generally mild and manageable.

Safety Profile:

•Most common side effects: joint pain, swelling, injection site reactions.

•Rare: increased glucose levels, potentially mild insulin resistance.

•Contraindicated in patients with active malignancy or pituitary tumors.