Kisspeptin 10 mg

Kisspeptin is a naturally occurring neuropeptide that plays a central physiological role in regulating reproductive hormone systems and related brain functions. It’s been the focus of significant research in endocrinology and reproductive biology. 

🧬 What Kisspeptin Is

• Type of peptide: Kisspeptin is a family of peptides encoded by the KISS1 gene. The full-length form is Kisspeptin-54, but shorter fragments like Kisspeptin-10 also retain biological activity.  
• Key receptor: It acts by binding to the G-protein coupled receptor GPR54, also called KISS1R.  
• Main biological role: Kisspeptin stimulates the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus — the first step of the reproductive hormone cascade.  

📊 Research & Potential Clinical Roles

Extensive research — including human clinical studies — has explored kisspeptin’s effects:

🔹 Reproductive hormone modulation

• In humans, kisspeptin administration increases LH and FSH, and in men may increase testosterone.  
• In women, it has been used experimentally to trigger ovulation in IVF protocols, potentially reducing risk of ovarian hyperstimulation syndrome compared with traditional triggers.  

🔹 Sexual desire and brain effects

• Studies show kisspeptin enhances limbic brain activity related to sexual arousal and bonding, with correlations to positive mood and reduced negative emotional processing.  

🔹 Reproductive disorders

• Early clinical research explores kisspeptin’s potential in conditions like hypothalamic amenorrhea, hypoactive sexual desire disorder, and PCOS-related anovulation.