Selank is a synthetic heptapeptide developed as a nootropic and anxiolytic agent — originally researched in Russia — with unique regulatory effects on the central nervous system. It’s a stable analogue of the natural immune peptide tuftsin (Thr-Lys-Pro-Arg) enhanced with an additional Pro-Gly-Pro sequence for increased metabolic stability and brain activity.
Selank is designed to support emotional balance, stress resilience, and cognitive performance through multiple mechanisms:
- GABAergic modulation: enhances brain inhibitory signaling for anxiety relief without sedation or dependency. Â
- Monoamine regulation: influences serotonin, dopamine, and norepinephrine pathways associated with mood, motivation, and stress response. Â
- Neurotrophic activity: promotes brain-derived neurotrophic factor (BDNF) expression, which supports learning, memory, and neural plasticity. Â
- Neuroimmune integration: retains some immunomodulatory properties from its tuftsin heritage and may help balance inflammatory signaling. Â







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