TB500 5 mg

🧬 What TB‑500 Is

• Name: TB‑500 (Thymosin Beta‑4 fragment)
• Type: Synthetic peptide derived from Thymosin β‑4, a naturally occurring protein involved in cell migration, tissue repair, and angiogenesis.
• Length: Typically a short peptide fragment of 43 amino acids, mimicking the active portion of thymosin β‑4.
• Research status: Experimental/research peptide; not FDA-approved for clinical use. It’s studied primarily in animal and preclinical models. (Peptide Sciences)

⚙️ Mechanism of Action

TB‑500 works primarily by modulating cellular and tissue-level repair processes:

1. Cell Migration (Chemotaxis)
   • Promotes movement of endothelial cells, keratinocytes, and fibroblasts toward sites of tissue injury.
   • Supports wound closure and tissue remodeling.
2. Angiogenesis
   • Stimulates formation of new blood vessels in damaged tissues, enhancing nutrient delivery and repair.
3. Cytoskeletal Regulation
   • Upregulates actin expression, helping cells move and stabilize damaged tissue structures.
4. Anti-Inflammatory Effects
   • May reduce excessive inflammatory signaling during tissue repair.

🧪 Research Applications

TB‑500 is primarily used in preclinical and animal research:

• Wound Healing & Skin Repair
  • Accelerates healing of cuts, burns, and surgical wounds in experimental models.
• Muscle, Ligament, & Tendon Repair
  • Studied for promoting regeneration and recovery after injury, including in sports medicine research.
• Cardiovascular & Angiogenesis Studies
  • Explored for potential roles in heart tissue repair and improving microvascular networks.
• Inflammatory Conditions
  • Works synergistically with other peptides like BPC‑157 or GHK‑Cu to modulate repair and inflammation.

TB‑500 is often combined with BPC‑157 in experimental protocols because BPC‑157 focuses more on vascular protection and gut/tendon healing, while TB‑500 enhances cellular migration and cytoskeletal function.